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Clear Your Mind - Blog
Constipation-Predominant Irritable Bowel Syndrome Associated to Hyperprolactinemia
Abstract Irritable bowel syndrome (IBS) is considered to be a physical disorder that mainly affects the bowel and is clinically...

Martin Mattsson
Jan 178 min read
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The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report
Alan C Logan 1 , Tracey M Beaulne Affiliations Expand PMID: 12410625 Abstract Recent investigations have shown that bacterial...

Martin Mattsson
Jan 171 min read
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Salt Loading Affects Cortisol Metabolism in Normotensive Subjects: Relationships with Salt Sensitivity
The Journal of Clinical Endocrinology & Metabolism , Volume 88, Issue 9, 1 September 2003, Pages 4180–4185, https://doi.org/10.1210/jc.20...

Martin Mattsson
Jan 172 min read
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Niacin ameliorates ulcerative colitis via prostaglandin D2‐mediated D prostanoid receptor 1 activation
Abstract Niacin, as an antidyslipidemic drug, elicits a strong flushing response by release of prostaglandin (PG) D2. However, whether...

Martin Mattsson
Jan 174 min read
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When Myth becomes Medical Fact People suffer unnecessarily; The Case of Mistaken Identity: How Pellagra now thought to be rare became known as Celiac Disease — A White Paper
When Myth becomes Medical Fact people suffer unnecessarily; the case of mistaken Identity: How Pellagra now thought to be rare became...

Martin Mattsson
Jan 1610 min read
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TREATMENT OF CIRRHOSIS OF THE LIVER BY A NUTRITIOUSDIET AND SUPPLEMENTS RICH IN VITAMIN B COMPLEX
TREATMENT OF CIRRHOSIS OF THE LIVER BY A NUTRITIOUS DIET AND SUPPLEMENTS RICH IN VITAMIN B COMPLEX By ARTHUR J. PATEK, JR. AND JOSEPH...

Martin Mattsson
Jan 162 min read
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To understand and manage anxiety: An evolutionary perspective
Anxiety is a natural reaction that humans have experienced throughout their evolutionary history. In today's society, understanding and...

Martin Mattsson
Jan 1612 min read
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Stimulation of platelet serotonin transport by substituted 1,4-naphthoquinone-induced oxidant stress
Abstract The effect of oxidant stress produced by redox cycling of substituted 1,4-naphthoquinones on the activity of platelet...

Martin Mattsson
Jan 161 min read
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Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO
Abstract Monoamine oxidase (MAO) catalyzes the oxidative deamination of biogenic and exogenous amines and its inhibitors have therapeutic...

Martin Mattsson
Jan 161 min read
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Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis
Abstract Osteoporosis is a disease of low bone mass most often caused by an increase in bone resorption that is not sufficiently...

Martin Mattsson
Jan 161 min read
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Inhibition of tryptophan hydroxylase abolishes fatigue induced by central tryptophan in exercising rats
Abstract Fatigue during prolonged exercise is related to brain monoamines concentrations, but the mechanisms underlying this relationship...

Martin Mattsson
Jan 161 min read
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Acetaminophen inhibits liver trytophan-2,3-dioxygenase activity with a concomitant rise in brain serotonin levels and a reduction in urinary 5-hydroxyindole acetic acid
Abstract The effect of the analgesic agent, acetaminophen was determined on rat forebrain serotonin levels as well as hepatic...

Martin Mattsson
Jan 161 min read
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Immobility induced by forced swimming in rats: effects of agents which modify central catecholamine and serotonin activity
Rats were forced to swim in a restricted space will rapidly cease apparent attempts to escape and adopt a characteristic posture which we...

Martin Mattsson
Jan 161 min read
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Forced swim stress activates rat hippocampal serotonergic neurotransmission involving a corticotropin-releasing hormone receptor-dependent mechanism
Abstract Serotonin is important for adequate coping with stress. Aberrant serotonin function is implicated in the aetiology of major...

Martin Mattsson
Jan 161 min read
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Increased blood-brain barrier permeability following acute short-term swimming exercise in conscious normotensive young rats
Abstract The status of the blood-brain barrier (BBB) was examined following short-term forced swimming (FS) exercise in younger rats (age...

Martin Mattsson
Jan 161 min read
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Thiamine as a neuroprotective agent after cardiac arrest
Abstract Aims Reduction of pyruvate dehydrogenase (PDH) activity in the brain is associated with neurological deficits in animals...

Martin Mattsson
Jan 162 min read
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High-dose thiamine improves the symptoms of fibromyalgia
Abstract Living with fibromyalgia means living with chronic pain, fatigue, sleep disorders and other associated key symptoms. To date,...

Martin Mattsson
Jan 168 min read
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Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex
Abstract Background and purpose: Based on the fact that traumatic brain injury is associated with mitochondrial dysfunction we aimed at...

Martin Mattsson
Jan 161 min read
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Delayed Influence of Spinal Cord Injury on the Amino Acids of NO• Metabolism in Rat Cerebral Cortex Is Attenuated by Thiamine
Abstract Severe spinal cord injuries (SCIs) result in chronic neuroinflammation in the brain, associated with the development of...

Martin Mattsson
Jan 1621 min read
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Mega-Dose Thiamine: Beyond Addressing “Deficiency”
Throughout the past few years, I have been prescribing thiamine more and more often for individuals with a range of different health...

Martin Mattsson
Jan 1613 min read
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